From Genome@Yale

Contents 1 2008 1.1 Genetics 425a/625a 1.1.1 Genomics I 1.1.2 Genomics II 1.1.3 Paper for Discussion 1.1.4 Take Home Questions 1.2 CBB752 1.2.1 ChIP-based technologies for interrogating the genome 2 2007 2.1 Genetics 425a/625a 2.1.1 Genomics I 2.1.2 Genomics II 2.1.3 Paper for Discussion 2.1.4 Take Home Question

2008

Genetics 425a/625a

Genomics I

• Lecture slides for November 10, 2008 lecture

Genomics II

• Lecture slides for November 12, 2008 lecture

Paper for Discussion

• article: Mikkelsen et al, Nature 448:553-560 (2007)
• optional reading
  • Mikkelsen et al, Nature 448:553-560 (2007) Supplementary Information

Take Home Questions

• Take Home Question #5 due December 1, 2008

CBB752

course outline

ChIP-based technologies for interrogating the genome

• Lecture slides

2007

Genetics 425a/625a

Genomics I

In this lecture, I cover how the human genome and other genomes were sequenced. I also cover comparative genomics as a tool to identify functional sequences. In the last section of the lecture, I introduce various genomics technologies utilized to interrogate various aspects of the genomic sequences.

• Lecture slides for November 7, 2007 lecture

Genomics II

In this lecture, I describe several examples of genome-wide technologies used to investigate regulatory mechanisms and to determine functions of genes in yeast and other organisms.

• Lecture slides for December 3, 2007 lecture

Paper for Discussion

• article: Collins et al, Nature 446:806-810 (2007)
• optional reading
  • Collins et al, Nature 446:806-810 (2007) Supplementary Information
  • Schuldiner et al, Methods 40:344-352 (2006)
  • Collins et al, Genome Biology 7:R63 (2006)

Take Home Question

• Take Home Question #6 due December 12, 2007